Antiretroviral Strategies to Prevent Mother-to-Child Transmission of HIV: Striking a Balance between Efficacy, Feasibility, and Resistance
نویسندگان
چکیده
Dara Lehman and colleagues discuss a randomized trial that found that adding up to a week of twice-daily zidovudine+lamivudine to single-dose nevirapine reduces the risk of resistance in mothers and infants.
منابع مشابه
Prevention of Mother to Child HIV Transmission
In Iran 8% of HIV- infected cases are women. Since most of them are young and in childbearing ages, in case of becoming pregnant and not receiving preventive measures, they can infect their child. Without Preventive measures transmission rate is 15 to 45 percent. Several factors such as sever stage of HIV and AIDS ,CD4 low count, high viral loud, acute retroviral phase, STDs, vaginal delivery, ...
متن کاملModelling HIV/AIDS epidemics in Botswana and India: impact of interventions to prevent transmission.
OBJECTIVE To describe a dynamic compartmental simulation model for Botswana and India, developed to identify the best strategies for preventing spread of HIV/AIDS. METHODS The following interventions were considered: a behavioural intervention focused on female sex workers; a conventional programme for the treatment of sexually transmitted infections; a programme for the prevention of mother-...
متن کاملChallenges and Proposed Actions for HIV/AIDS Control among Children in Iran
It is estimated globally 3.2 million children were living with HIV in 2014, that mostly in sub-Saharan Africa. However, the majority of them infected to HIV from their mothers during pregnancy, during delivery or breastfeeding (1). Antiretroviral therapy (ART) use during and after pregnancy is essential for prevention of mother-to-child transmission (PMTCT) of HIV (2). In the absence of any in...
متن کاملProphylactic antiretroviral regimens for prevention of mother-to-child transmission of HIV in resource-limited settings.
PURPOSE OF REVIEW With the large international mobilization against HIV/AIDS, more HIV-infected people in resource-limited settings have access to antiretroviral therapy, including pregnant women. The relevance of simplified prophylactic antiretroviral regimens for the prevention of mother-to-child transmission of HIV may become questionable due to their lower efficacy and their higher risk of ...
متن کاملThe controversies of nevirapine for preventing mother-to-child HIV transmission.
The efficacy of antiretroviral therapy to prevent motherto-child HIV transmission (MTCT) was first established in 1994. In that study by Connor and colleagues (PACTG 076) both mother and infant were treated with long courses of zidovudine, which reduced HIV transmission from 25 to 8% [1]. Since then, improved interventions in industrialized nations have further reduced MTCT rates to less than 2...
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عنوان ژورنال:
دوره 6 شماره
صفحات -
تاریخ انتشار 2009